Pharmaceutical Investigations and Technology (PIT) is a group within Global Analytical Technology (GAT) department in the commercial Quality organization within Bristol-Myers Squibb. The PIT group has been a key part in BMS for 30 + years in providing analytical support for commercial manufacturing and in pharmaceutical forensics. This include particulate and foreign matter characterization in pharmaceutical products and screening counterfeit drugs. Several analytical tools and techniques are used by PIT to support the pharmaceutical forensics. These include Energy Dispersive X-ray spectroscopy (EDS/EDX), Scanning Electron Microscopy (SEM), microscopes, Raman, Infrared (IR) and Near Infrared (NIR) micro-spectroscopy. Energy Dispersive X-Ray spectroscopy (EDS/EDX) is a powerful tool in the evaluation of foreign and particulate matter from a variety of processes and products. Coupled with an SEM, the technique provides a qualitative analysis of the elemental composition of particulate matter on the micron size range. The data from EDS can also be used for semi-quantitative applications when certain analytical criteria are met. Confocal Raman and NIR chemical imaging can successfully determine the chemical composition of the unwanted particulate foreign matter in finished pharmaceutical drug products. A point-by-point mapping technique along with CLS (Classical Least Square) fitting can be used to acquire a Raman chemical map of foreign particle surface and to identify the chemical components. In addition, both Raman and NIR spectroscopy have been widely used to rapidly screen counterfeit drugs. This talk will feature all the analytical techniques used by PIT and how the results are used in resolving manufacturing issues and to protect patients from counterfeit drugs.

Hora

16:00 - 17:00 hs GMT+1

Organizador

BioPharma Asia Magazine
Compartir
Enviar a un amigo
Mi email *
Email destinatario *
Comentario *
Repite estos números *
Control de seguridad
Mayo / 2020 1140 webinars
Lunes
Martes
Miércoles
Jueves
Viernes
Sábado
Domingo
Lun 27 de Mayo de 2020
Mar 28 de Mayo de 2020
Mié 29 de Mayo de 2020
Jue 30 de Mayo de 2020
Vie 01 de Mayo de 2020
Sáb 02 de Mayo de 2020
Dom 03 de Mayo de 2020
Lun 04 de Mayo de 2020
Mar 05 de Mayo de 2020
Mié 06 de Mayo de 2020
Jue 07 de Mayo de 2020
Vie 08 de Mayo de 2020
Sáb 09 de Mayo de 2020
Dom 10 de Mayo de 2020
Lun 11 de Mayo de 2020
Mar 12 de Mayo de 2020
Mié 13 de Mayo de 2020